diff --git a/clang/CMakeLists.txt b/clang/CMakeLists.txt
index 61fd913a2a53..84984f75b5f8 100644
--- a/clang/CMakeLists.txt
+++ b/clang/CMakeLists.txt
@@ -502,6 +502,7 @@ if( CLANG_INCLUDE_TESTS )
       )
   endif()
   add_subdirectory(utils/perf-training)
+  add_subdirectory(bindings/python/tests)
 endif()
 
 option(CLANG_INCLUDE_DOCS "Generate build targets for the Clang docs."
diff --git a/clang/bindings/python/tests/CMakeLists.txt b/clang/bindings/python/tests/CMakeLists.txt
new file mode 100644
index 000000000000..66758a3f2aac
--- /dev/null
+++ b/clang/bindings/python/tests/CMakeLists.txt
@@ -0,0 +1,7 @@
+# Test target to run Python test suite from main build.
+
+add_custom_target(check-clang-python
+	COMMAND CLANG_LIBRARY_PATH=$<TARGET_FILE_DIR:libclang> ${PYTHON_EXECUTABLE} -m unittest discover
+	DEPENDS libclang
+	WORKING_DIRECTORY ${CMAKE_CURRENT_SOURCE_DIR}/..)
+add_dependencies(check-all check-clang-python)