Gratis for personal use, but commercial for business use. Appears to work without a license key but offers the ability for a free personal-use key http://www.grapefruit.ch/iBackup/donation.html
Backup is a simple to use backup/restore utility.
It backups and restores user data and system and applications settings,
e.g. System Preferences, Mail, iPhoto, iTunes, but also 3rd party
applications settings, more than 250 plugins for backup application
settings are available, which allow you to restore the settings and
data of one application or to restore an earlier point in time.